What is Semax?
Semax is a research peptide in the Cognitive & Nootropic class. ACTH(4-10) analog; elevates BDNF and modulates monoaminergic tone. It is studied at per-dose ranges of 250–500 mcg × 2–3 / day (intranasal) (3.5–10 mg weekly), administered 2–3× daily intranasal over cycles of 14 days on / 14 off. Supplied in Thailand by Thailand Peptides — Bangkok-based, research use only.
Heptapeptide analog of ACTH fragment. Russian-registered for stroke recovery; studied for BDNF and NGF expression.
Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.
How does Semax work?
Primary mechanism: ACTH(4-10) analog; elevates BDNF and modulates monoaminergic tone. Research on Semax implicates downstream effects on related signalling cascades, with magnitude and clinical relevance dependent on dose, timing, and individual pharmacogenomic factors.
Receptor binding affinity and post-receptor signalling for Semax remain areas of active investigation; several proposed effects within the Cognitive & Nootropic class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.
Semax dosage & protocol
Reference protocol for Semax (research context only, drawn from published literature):
- Per dose: 250–500 mcg × 2–3 / day (intranasal)
- Weekly total: 3.5–10 mg
- Frequency: 2–3× daily intranasal
- Cycle: 14 days on / 14 off
Stacking Semax
Commonly referenced pairing with Semax: Selank. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a Semax stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.
Contraindications
None established. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.
Semax — common questions
What is Semax and what is it used for in research?
How does Semax work?
What is the typical Semax research dose?
Where can I buy Semax in Thailand?
How fast can Semax be delivered in Thailand?
Citations
- Dolotov OV, et al. Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor. J Neurochem. 2006. PMID: 16635254
References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.