Quick answers

What is Semax and what is it used for in research?
Semax is classified within the Cognitive & Nootropic group. Heptapeptide analog of ACTH fragment. Russian-registered for stroke recovery; studied for BDNF and NGF expression. Research applications focus on the pathways outlined below. All references on this page describe published research only, Semax is supplied for in-vitro and laboratory use, not for human consumption.
How does Semax work?
Primary mechanism: ACTH(4-10) analog; elevates BDNF and modulates monoaminergic tone. Downstream effects depend on dose, timing, and the biological system under investigation. Receptor binding and post-receptor signalling for Semax remain areas of active study, and several proposed effects are supported only by preclinical data.
What is the typical Semax research dose?
Published research protocols for Semax describe per-dose ranges of 250–500 mcg × 2–3 / day (intranasal), with a weekly total near 3.5–10 mg, administered 2–3× daily intranasal. Typical cycle: 14 days on / 14 off. These ranges reflect the literature and are not dosing recommendations for any individual.
Where can I buy Semax in Thailand?
Semax is supplied by Thailand Peptides, a Bangkok-based research-peptide supplier. Orders are placed directly via WhatsApp to the Bangkok research desk, no cart, no account, no forms. Pricing and shipping are provided on request. Open a line with the research desk →
How fast can Semax be delivered in Thailand?
Same-week delivery across Thailand is standard for orders confirmed within business hours (GMT+7, Monday–Saturday). Bangkok metro deliveries typically arrive within 1–3 business days; other provinces within 3–5. Regional Southeast Asia shipping is available on request.

What is Semax?

Semax is a research peptide in the Cognitive & Nootropic class. ACTH(4-10) analog; elevates BDNF and modulates monoaminergic tone. It is studied at per-dose ranges of 250–500 mcg × 2–3 / day (intranasal) (3.5–10 mg weekly), administered 2–3× daily intranasal over cycles of 14 days on / 14 off. Supplied in Thailand by Thailand Peptides, Bangkok-based, research use only.

Heptapeptide analog of ACTH fragment. Russian-registered for stroke recovery; studied for BDNF and NGF expression.

Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.

How does Semax work?

Semax is a synthetic analogue of the ACTH(4-10) fragment with a C-terminal Pro-Gly-Pro extension that confers proteolytic stability. Research describes binding to brain BDNF- and NGF-related neurotrophin pathways, elevation of hippocampal BDNF expression, and modulation of monoaminergic (dopaminergic, serotonergic) tone. Russian registration is for ischaemic-stroke recovery and cognitive indications.

Receptor binding affinity and post-receptor signalling for Semax remain areas of active investigation; several proposed effects within the Cognitive & Nootropic class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.

Semax pharmacokinetics

Half-life
Short intranasal plasma half-life; central nervous system exposure persists beyond plasma clearance.
Bioavailability
Intranasal route provides direct nose-to-brain delivery; oral route not used.
Route of administration
Intranasal drops, 2–3 times daily in research and clinical protocols.
Metabolic clearance
Rapid peripheral proteolytic degradation.

Semax research timeline

  1. 2006 Dolotov et al., Semax binds specifically and elevates brain-derived neurotrophic factor (J Neurochem).

Semax dosage & protocol

Reference protocol for Semax (research context only, drawn from published literature):

  • Per dose: 250–500 mcg × 2–3 / day (intranasal)
  • Weekly total: 3.5–10 mg
  • Frequency: 2–3× daily intranasal
  • Cycle: 14 days on / 14 off

Semax injection & handling

Reconstitution
Typically supplied as intranasal solution; research material reconstituted in saline for intranasal delivery.
Storage
Refrigerated at 2–8 °C.
Sites used in the research literature
Intranasal, 1–2 drops per nostril 2–3 times daily in published protocols.

Handling notes reflect methods used in published research protocols, not medical dosing guidance.

Order Semax
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Stacking Semax

Commonly referenced pairing with Semax: Selank. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a Semax stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.

Contraindications

None established. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.

Research summaries

Further reading

Citations

  1. Dolotov OV, et al. Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor. J Neurochem. 2006. PMID: 16635254

References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.