Quick answers
What is Selank and what is it used for in research?
How does Selank work?
What is the typical Selank research dose?
Where can I buy Selank in Thailand?
How fast can Selank be delivered in Thailand?
What is Selank?
Selank is a research peptide in the Cognitive & Nootropic class. Tuftsin analog; anxiolytic and nootropic activity via enkephalin modulation. It is studied at per-dose ranges of 250–500 mcg × 2 / day (intranasal) (3.5–7 mg weekly), administered 2× daily intranasal over cycles of 14 days on / 14 off. Supplied in Thailand by Thailand Peptides, Bangkok-based, research use only.
Heptapeptide derived from tuftsin. Russian-registered anxiolytic; modulates GABAergic and enkephalinergic systems.
Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.
How does Selank work?
Selank is a synthetic heptapeptide analogue of the natural tetrapeptide tuftsin. It produces anxiolytic and nootropic effects in animal models without the sedation or dependence liability of benzodiazepines. Research describes modulation of GABAergic and enkephalinergic systems, elevated BDNF expression in hippocampus, and transcriptomic changes in rat hippocampus and spleen after acute dosing.
Receptor binding affinity and post-receptor signalling for Selank remain areas of active investigation; several proposed effects within the Cognitive & Nootropic class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.
Selank pharmacokinetics
- Half-life
- Very short, approximately 5 minutes plasma half-life following intranasal administration.
- Bioavailability
- Intranasal bioavailability is the standard route; IV research routes have been described.
- Route of administration
- Intranasal drops, 2–3 times daily in research protocols.
- Metabolic clearance
- Rapid proteolytic degradation; metabolite activity partially characterised.
Selank research timeline
- 2010 Kolomin et al., transcriptomic response of rat hippocampus and spleen to acute Selank (Dokl Biochem Biophys).
Selank dosage & protocol
Reference protocol for Selank (research context only, drawn from published literature):
- Per dose: 250–500 mcg × 2 / day (intranasal)
- Weekly total: 3.5–7 mg
- Frequency: 2× daily intranasal
- Cycle: 14 days on / 14 off
Selank injection & handling
- Reconstitution
- Typically supplied as intranasal solution; lyophilised material reconstituted in saline with a preservative for intranasal use.
- Storage
- Refrigerated at 2–8 °C; stored away from light.
- Sites used in the research literature
- Intranasal, 1–2 drops per nostril 2–3 times daily in published protocols.
Handling notes reflect methods used in published research protocols, not medical dosing guidance.
Stacking Selank
Commonly referenced pairing with Selank: Semax. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a Selank stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.
Contraindications
None established. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.
Further reading
- Fundamentals · 9 min read Understanding Peptide Reconstitution: A Research Guide Practical guide to reconstituting lyophilized research peptides. Choosing a diluent, concentration math, injection-site-ready volumes, and the literature…
- Fundamentals · 10 min read Injection Site Selection in Peptide Research How injection site choice affects peptide absorption: abdomen, thigh, upper arm, and the research literature on site-driven pharmacokinetic differences…
- Buyer guide · 9 min read Best Peptides for Cognitive Function: A Research Comparison Research comparison of Semax, Selank, Cerebrolysin, and DSIP for cognitive-function and neurotrophic research.
- Deep dive · 10 min read Semax and Selank: BDNF Modulation in Research Models Deep-dive into the BDNF pharmacology of Semax and Selank. How two Russian-developed neuropeptides converge on BDNF and NGF expression in rat hippocampus…
Citations
- Kolomin T, et al. Transcriptomic response of rat hippocampus and spleen cells to single administration of Selank. Dokl Biochem Biophys. 2010. PMID: 20380151
References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.