Quick answers

What is DSIP and what is it used for in research?
DSIP is classified within the Cognitive & Nootropic group. Nonapeptide originally isolated from rabbit cerebrospinal fluid. Investigated for sleep quality and chronic-pain modulation. Research applications focus on the pathways outlined below. All references on this page describe published research only, DSIP is supplied for in-vitro and laboratory use, not for human consumption.
How does DSIP work?
Primary mechanism: Delta-sleep-inducing peptide; modulates sleep architecture. Downstream effects depend on dose, timing, and the biological system under investigation. Receptor binding and post-receptor signalling for DSIP remain areas of active study, and several proposed effects are supported only by preclinical data.
What is the typical DSIP research dose?
Published research protocols for DSIP describe per-dose ranges of 100–200 mcg / night, with a weekly total near 0.7–1.4 mg, administered nightly sc. Typical cycle: ongoing as needed. These ranges reflect the literature and are not dosing recommendations for any individual.
Where can I buy DSIP in Thailand?
DSIP is supplied by Thailand Peptides, a Bangkok-based research-peptide supplier. Orders are placed directly via WhatsApp to the Bangkok research desk, no cart, no account, no forms. Pricing and shipping are provided on request. Open a line with the research desk →
How fast can DSIP be delivered in Thailand?
Same-week delivery across Thailand is standard for orders confirmed within business hours (GMT+7, Monday–Saturday). Bangkok metro deliveries typically arrive within 1–3 business days; other provinces within 3–5. Regional Southeast Asia shipping is available on request.

What is DSIP?

DSIP is a research peptide in the Cognitive & Nootropic class. Delta-sleep-inducing peptide; modulates sleep architecture. It is studied at per-dose ranges of 100–200 mcg / night (0.7–1.4 mg weekly), administered nightly sc over cycles of ongoing as needed. Supplied in Thailand by Thailand Peptides, Bangkok-based, research use only.

Nonapeptide originally isolated from rabbit cerebrospinal fluid. Investigated for sleep quality and chronic-pain modulation.

Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.

How does DSIP work?

DSIP (delta-sleep-inducing peptide) is a nonapeptide originally isolated from rabbit cerebrospinal fluid. Preclinical work describes modulation of NREM sleep architecture, attenuation of stress-induced HPA-axis activation, and effects on chronic-pain endpoints. Specific receptor and downstream signalling pathways remain incompletely defined in the primary literature.

Receptor binding affinity and post-receptor signalling for DSIP remain areas of active investigation; several proposed effects within the Cognitive & Nootropic class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.

DSIP pharmacokinetics

Half-life
Limited published human pharmacokinetic data; animal studies describe short plasma half-life.
Bioavailability
SC and IV routes used in research; oral activity not established.
Route of administration
Subcutaneous injection nightly in research protocols investigating sleep architecture.
Metabolic clearance
Proteolytic clearance; precise metabolic pathways incompletely characterised.

DSIP research timeline

  1. 1977 Schoenenberger & Monnier, isolation and characterisation of DSIP from rabbit cerebrospinal fluid.
  2. 2000s Sequential pharmacology studies describe sleep-architecture and stress-modulation endpoints.

DSIP dosage & protocol

Reference protocol for DSIP (research context only, drawn from published literature):

  • Per dose: 100–200 mcg / night
  • Weekly total: 0.7–1.4 mg
  • Frequency: Nightly SC
  • Cycle: Ongoing as needed

DSIP injection & handling

Reconstitution
Typical research prep: 5 mg vial + 2–3 mL bacteriostatic water, yielding ~1.67–2.5 mg/mL.
Storage
Lyophilised powder at −20 °C; reconstituted solution refrigerated for up to 4 weeks in research protocols.
Sites used in the research literature
Subcutaneous abdomen, administered in the evening per published sleep-architecture protocols.

Handling notes reflect methods used in published research protocols, not medical dosing guidance.

Order DSIP
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Stacking DSIP

Commonly referenced pairing with DSIP: Monotherapy. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a DSIP stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.

Contraindications

Limited clinical data. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.

Further reading

Compare DSIP with: Selank

Citations

  1. Kovalzon VM, Strekalova TV. Delta sleep-inducing peptide (DSIP): a still unresolved riddle. J Neurochem. 2006. PMID: 16539679
  2. Graf MV, Kastin AJ. DSIP affects adrenergic stimulation of rat pineal N-acetyltransferase activity. Peptides. 1986. PMID: 3562314

References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.