Quick answers

What is TB-500 and what is it used for in research?
TB-500 is classified within the Healing & Recovery group. Synthetic analog of the TB4 actin-sequestering peptide. Studied for myocardial, dermal and musculoskeletal repair. Research applications focus on the pathways outlined below. All references on this page describe published research only, TB-500 is supplied for in-vitro and laboratory use, not for human consumption.
How does TB-500 work?
Primary mechanism: Fragment of Thymosin-β4; upregulates actin polymerisation and angiogenesis. Downstream effects depend on dose, timing, and the biological system under investigation. Receptor binding and post-receptor signalling for TB-500 remain areas of active study, and several proposed effects are supported only by preclinical data.
What is the typical TB-500 research dose?
Published research protocols for TB-500 describe per-dose ranges of 2–2.5 mg × 2 / week, with a weekly total near 4–5 mg, administered twice-weekly sc. Typical cycle: 4–6 weeks loading, 2 mg/wk maintenance. These ranges reflect the literature and are not dosing recommendations for any individual.
Where can I buy TB-500 in Thailand?
TB-500 is supplied by Thailand Peptides, a Bangkok-based research-peptide supplier. Orders are placed directly via WhatsApp to the Bangkok research desk, no cart, no account, no forms. Pricing and shipping are provided on request. Open a line with the research desk →
How fast can TB-500 be delivered in Thailand?
Same-week delivery across Thailand is standard for orders confirmed within business hours (GMT+7, Monday–Saturday). Bangkok metro deliveries typically arrive within 1–3 business days; other provinces within 3–5. Regional Southeast Asia shipping is available on request.

What is TB-500?

TB-500 is a research peptide in the Healing & Recovery class. Fragment of Thymosin-β4; upregulates actin polymerisation and angiogenesis. It is studied at per-dose ranges of 2–2.5 mg × 2 / week (4–5 mg weekly), administered twice-weekly sc over cycles of 4–6 weeks loading, 2 mg/wk maintenance. Supplied in Thailand by Thailand Peptides, Bangkok-based, research use only.

Synthetic analog of the TB4 actin-sequestering peptide. Studied for myocardial, dermal and musculoskeletal repair.

Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.

How does TB-500 work?

The thymosin-β4 analogue sequesters G-actin and regulates actin polymerisation dynamics, enabling cell migration into wound beds. Downstream effects include ILK/Akt-mediated pro-survival signalling, laminin-5 and VEGF upregulation, and angiogenesis. The enzymatically released tetrapeptide Ac-SDKP contributes anti-fibrotic and pro-angiogenic activity independent of the parent molecule.

Receptor binding affinity and post-receptor signalling for TB-500 remain areas of active investigation; several proposed effects within the Healing & Recovery class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.

TB-500 pharmacokinetics

Half-life
Systemic half-life in the low-hours range after parenteral dosing in preclinical work.
Bioavailability
High bioavailability via SC and IM routes in animal models; oral route not used in published research.
Route of administration
Subcutaneous and intramuscular injection are the routes used in preclinical wound-healing studies.
Metabolic clearance
Cleared predominantly via renal pathways; the naturally occurring Ac-SDKP fragment is enzymatically generated during metabolism.

TB-500 research timeline

  1. 1999 Malinda et al., thymosin β4 accelerates wound healing in dermal models (J Invest Dermatol).
  2. 2010 Crockford et al., structure, function, and biological properties review (Ann N Y Acad Sci).
  3. 2012 Goldstein et al., multi-functional regenerative peptide review (Expert Opin Biol Ther).

TB-500 dosage & protocol

Reference protocol for TB-500 (research context only, drawn from published literature):

  • Per dose: 2–2.5 mg × 2 / week
  • Weekly total: 4–5 mg
  • Frequency: Twice-weekly SC
  • Cycle: 4–6 weeks loading, 2 mg/wk maintenance

TB-500 injection & handling

Reconstitution
Typical research prep: 5 mg vial + 2–2.5 mL bacteriostatic water, producing 2–2.5 mg/mL.
Storage
Lyophilised powder at −20 °C long-term; reconstituted solution refrigerated and used within 4 weeks in published protocols.
Sites used in the research literature
Subcutaneous abdominal injection is the most common research site; intramuscular sites also documented.

Handling notes reflect methods used in published research protocols, not medical dosing guidance.

Order TB-500
Ready to order? WhatsApp the Bangkok research desk, pricing and availability confirmed within the chat.
Ask about TB-500 ≥98% HPLC purity · supplier COA on file · Bangkok-based

Stacking TB-500

Commonly referenced pairing with TB-500: BPC-157. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a TB-500 stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.

Contraindications

Active malignancy. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.

Further reading

Citations

  1. Goldstein AL, et al. Thymosin β4: a multi-functional regenerative peptide. Expert Opin Biol Ther. 2012. PMID: 22074294
  2. Malinda KM, et al. Thymosin β4 accelerates wound healing. J Invest Dermatol. 1999. PMID: 10469335
  3. Crockford D, et al. Thymosin β4: structure, function, and biological properties. Ann N Y Acad Sci. 2010. PMID: 20536467

References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.