What is 5-Amino-1MQ?

5-Amino-1MQ is a research peptide in the Body Recomposition class. Small-molecule NNMT inhibitor; preserves methyl donors and raises cellular NAD+. It is studied at per-dose ranges of 2–5 mg / day (14–35 mg weekly), administered oral daily over cycles of 8–12 weeks. Supplied in Thailand by Thailand Peptides — Bangkok-based, research use only.

Selective, membrane-permeable NNMT (nicotinamide N-methyltransferase) inhibitor. In preclinical models, inhibition of NNMT in adipose tissue preserves SAM/methyl donors, elevates cellular NAD+, and reduces adiposity while improving metabolic flexibility.

Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.

How does 5-Amino-1MQ work?

Primary mechanism: Small-molecule NNMT inhibitor; preserves methyl donors and raises cellular NAD+. Research on 5-Amino-1MQ implicates downstream effects on related signalling cascades, with magnitude and clinical relevance dependent on dose, timing, and individual pharmacogenomic factors.

Receptor binding affinity and post-receptor signalling for 5-Amino-1MQ remain areas of active investigation; several proposed effects within the Body Recomposition class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.

5-Amino-1MQ dosage & protocol

Reference protocol for 5-Amino-1MQ (research context only, drawn from published literature):

  • Per dose: 2–5 mg / day
  • Weekly total: 14–35 mg
  • Frequency: Oral daily
  • Cycle: 8–12 weeks

Stacking 5-Amino-1MQ

Commonly referenced pairing with 5-Amino-1MQ: Monotherapy. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a 5-Amino-1MQ stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.

Contraindications

Limited human safety data. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.

5-Amino-1MQ — common questions

What is 5-Amino-1MQ and what is it used for in research?
5-Amino-1MQ is classified within the Body Recomposition group. Selective, membrane-permeable NNMT (nicotinamide N-methyltransferase) inhibitor. In preclinical models, inhibition of NNMT in adipose tissue preserves SAM/methyl donors, elevates cellular NAD+, and reduces adiposity while improving metabolic flexibility. Research applications focus on the pathways outlined below. All references on this page describe published research only — 5-Amino-1MQ is supplied for in-vitro and laboratory use, not for human consumption.
How does 5-Amino-1MQ work?
Primary mechanism: Small-molecule NNMT inhibitor; preserves methyl donors and raises cellular NAD+. Downstream effects depend on dose, timing, and the biological system under investigation. Receptor binding and post-receptor signalling for 5-Amino-1MQ remain areas of active study, and several proposed effects are supported only by preclinical data.
What is the typical 5-Amino-1MQ research dose?
Published research protocols for 5-Amino-1MQ describe per-dose ranges of 2–5 mg / day, with a weekly total near 14–35 mg, administered oral daily. Typical cycle: 8–12 weeks. These ranges reflect the literature and are not dosing recommendations for any individual.
Where can I buy 5-Amino-1MQ in Thailand?
5-Amino-1MQ is supplied by Thailand Peptides, a Bangkok-based research-peptide supplier. Orders are placed directly via WhatsApp to the Bangkok research desk — no cart, no account, no forms. Pricing and shipping are provided on request. Open a line with the research desk →
How fast can 5-Amino-1MQ be delivered in Thailand?
Same-week delivery across Thailand is standard for orders confirmed within business hours (GMT+7, Monday–Saturday). Bangkok metro deliveries typically arrive within 1–3 business days; other provinces within 3–5. Regional Southeast Asia shipping is available on request.

Citations

  1. Neelakantan H, et al. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochem Pharmacol. 2018. PMID: 29155147

References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.