Quick answers

What is SS-31 and what is it used for in research?
SS-31 is classified within the Body Recomposition group. Aromatic-cationic tetrapeptide that selectively concentrates in the inner mitochondrial membrane via cardiolipin binding. Preserves cristae architecture, restores ATP synthesis, and reduces reactive oxygen species in stressed mitochondria. Research applications focus on the pathways outlined below. All references on this page describe published research only, SS-31 is supplied for in-vitro and laboratory use, not for human consumption.
How does SS-31 work?
Primary mechanism: Mitochondria-targeted tetrapeptide (Elamipretide); binds cardiolipin to preserve cristae structure and reduce ROS leakage. Downstream effects depend on dose, timing, and the biological system under investigation. Receptor binding and post-receptor signalling for SS-31 remain areas of active study, and several proposed effects are supported only by preclinical data.
What is the typical SS-31 research dose?
Published research protocols for SS-31 describe per-dose ranges of 1–3 mg / day, with a weekly total near 7–21 mg, administered daily sc. Typical cycle: 4–12 weeks. These ranges reflect the literature and are not dosing recommendations for any individual.
Where can I buy SS-31 in Thailand?
SS-31 is supplied by Thailand Peptides, a Bangkok-based research-peptide supplier. Orders are placed directly via WhatsApp to the Bangkok research desk, no cart, no account, no forms. Pricing and shipping are provided on request. Open a line with the research desk →
How fast can SS-31 be delivered in Thailand?
Same-week delivery across Thailand is standard for orders confirmed within business hours (GMT+7, Monday–Saturday). Bangkok metro deliveries typically arrive within 1–3 business days; other provinces within 3–5. Regional Southeast Asia shipping is available on request.

What is SS-31?

SS-31 is a research peptide in the Body Recomposition class. Mitochondria-targeted tetrapeptide (Elamipretide); binds cardiolipin to preserve cristae structure and reduce ROS leakage. It is studied at per-dose ranges of 1–3 mg / day (7–21 mg weekly), administered daily sc over cycles of 4–12 weeks. Supplied in Thailand by Thailand Peptides, Bangkok-based, research use only.

Aromatic-cationic tetrapeptide that selectively concentrates in the inner mitochondrial membrane via cardiolipin binding. Preserves cristae architecture, restores ATP synthesis, and reduces reactive oxygen species in stressed mitochondria.

Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.

How does SS-31 work?

Primary mechanism: Mitochondria-targeted tetrapeptide (Elamipretide); binds cardiolipin to preserve cristae structure and reduce ROS leakage. Research on SS-31 implicates downstream effects on related signalling cascades, with magnitude and clinical relevance dependent on dose, timing, and individual pharmacogenomic factors.

Receptor binding affinity and post-receptor signalling for SS-31 remain areas of active investigation; several proposed effects within the Body Recomposition class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.

SS-31 dosage & protocol

Reference protocol for SS-31 (research context only, drawn from published literature):

  • Per dose: 1–3 mg / day
  • Weekly total: 7–21 mg
  • Frequency: Daily SC
  • Cycle: 4–12 weeks
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Stacking SS-31

Commonly referenced pairing with SS-31: MOTS-c, NAD+. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a SS-31 stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.

Contraindications

Limited long-term human data. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.

Citations

  1. Mitchell W, Tamucci JD, Ng EL, et al. The mitochondria-targeted peptide SS-31 binds lipid bilayers and modulates surface electrostatics as a key component of its mechanism of action (Szeto group). J Biol Chem. 2020. PMID: 32273339
  2. Birk AV, et al. The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin. J Am Soc Nephrol. 2013. PMID: 23813215
  3. Karaa A, et al. Randomized dose-escalation trial of elamipretide in adults with primary mitochondrial myopathy. Neurology. 2018. PMID: 29500292

References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.