Quick answers
What is AOD-9604 and what is it used for in research?
How does AOD-9604 work?
What is the typical AOD-9604 research dose?
Where can I buy AOD-9604 in Thailand?
How fast can AOD-9604 be delivered in Thailand?
What is AOD-9604?
AOD-9604 is a research peptide in the Body Recomposition class. C-terminal fragment of hGH (176–191); investigated for lipolytic activity. It is studied at per-dose ranges of 300 mcg / day (1.5–2 mg weekly), administered daily sc (fasted) over cycles of 12 weeks on / 4 off. Supplied in Thailand by Thailand Peptides, Bangkok-based, research use only.
16-amino-acid fragment of hGH. Preclinical data suggests selective lipolysis without affecting IGF-1.
Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.
How does AOD-9604 work?
AOD-9604 is a synthetic analogue of the C-terminal residues 176–191 of human growth hormone. In preclinical models it produces lipolytic activity and reduces adipose tissue in obese rodents without the IGF-1 elevation, insulin-sensitivity changes, or tissue growth associated with full-length hGH. The lipolytic pathway appears to act independently of classical β-adrenergic receptors in several published studies.
Receptor binding affinity and post-receptor signalling for AOD-9604 remain areas of active investigation; several proposed effects within the Body Recomposition class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.
AOD-9604 pharmacokinetics
- Half-life
- Short systemic half-life after SC dosing; oral bioavailability is low in published work.
- Bioavailability
- SC route is standard in research; oral formulations explored but with limited absorption.
- Route of administration
- Subcutaneous injection, typically once daily in a fasted state in research protocols.
- Metabolic clearance
- Proteolytic clearance of the 16-aa fragment; no accumulation reported.
AOD-9604 research timeline
- 2001 Heffernan et al., hGH fragment AOD9604 lipolytic mechanism in mouse adipocytes (Endocrinology).
AOD-9604 dosage & protocol
Reference protocol for AOD-9604 (research context only, drawn from published literature):
- Per dose: 300 mcg / day
- Weekly total: 1.5–2 mg
- Frequency: Daily SC (fasted)
- Cycle: 12 weeks on / 4 off
AOD-9604 injection & handling
- Reconstitution
- Typical research prep: 5 mg vial + 2 mL bacteriostatic water, yielding 2.5 mg/mL.
- Storage
- Lyophilised powder at −20 °C; reconstituted solution refrigerated for up to 4 weeks in research protocols.
- Sites used in the research literature
- Subcutaneous abdomen on an empty stomach per published protocols.
Handling notes reflect methods used in published research protocols, not medical dosing guidance.
Stacking AOD-9604
Commonly referenced pairing with AOD-9604: GHRH analog. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a AOD-9604 stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.
Contraindications
Active malignancy. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.
Further reading
- Fundamentals · 9 min read Understanding Peptide Reconstitution: A Research Guide Practical guide to reconstituting lyophilized research peptides. Choosing a diluent, concentration math, injection-site-ready volumes, and the literature…
- Fundamentals · 10 min read Injection Site Selection in Peptide Research How injection site choice affects peptide absorption: abdomen, thigh, upper arm, and the research literature on site-driven pharmacokinetic differences…
- Buyer guide · 10 min read Best Peptides for Fat Loss: A Research Comparison Research comparison of Semaglutide, Tirzepatide, Retatrutide, AOD-9604, and 5-Amino-1MQ for body-composition research.
- Deep dive · 10 min read AOD-9604 and Lipolysis: Research Mechanism Overview AOD-9604 deep-dive: hGH 176-191 fragment, β3-AR-independent lipolysis, no IGF-1 elevation, body-composition research. Bangkok research-grade.
Citations
- Heffernan M, et al. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and β3-AR knock-out mice. Endocrinology. 2001. PMID: 11713213
References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.