What is Ipamorelin?
Ipamorelin is a research peptide in the GH Secretagogue class. Selective ghrelin-receptor agonist; GH-specific with minimal cortisol or prolactin effect. It is studied at per-dose ranges of 200–300 mcg × 2–3 / day (4–6 mg weekly), administered 2–3× daily sc over cycles of 12 weeks on / 4 off. Supplied in Thailand by Thailand Peptides — Bangkok-based, research use only.
Pentapeptide GHS. Acts on GHS-R1a without appreciable effect on cortisol, prolactin, or appetite at standard research doses.
Published and preclinical data are summarised below; dose ranges shown reflect protocols in the research literature and should be interpreted accordingly.
How does Ipamorelin work?
Primary mechanism: Selective ghrelin-receptor agonist; GH-specific with minimal cortisol or prolactin effect. Research on Ipamorelin implicates downstream effects on related signalling cascades, with magnitude and clinical relevance dependent on dose, timing, and individual pharmacogenomic factors.
Receptor binding affinity and post-receptor signalling for Ipamorelin remain areas of active investigation; several proposed effects within the GH Secretagogue class are currently supported only by in-vitro or rodent data, and should be interpreted accordingly.
Ipamorelin dosage & protocol
Reference protocol for Ipamorelin (research context only, drawn from published literature):
- Per dose: 200–300 mcg × 2–3 / day
- Weekly total: 4–6 mg
- Frequency: 2–3× daily SC
- Cycle: 12 weeks on / 4 off
Stacking Ipamorelin
Commonly referenced pairing with Ipamorelin: CJC-1295, Tesamorelin. Stacking rationale should be grounded in complementary mechanisms, not additive speculation; interactions at shared receptors or enzymatic pathways should be accounted for. Both compounds in a Ipamorelin stack are supplied by Thailand Peptides on the same order via the Bangkok research desk.
Contraindications
Active malignancy. Additional caution is warranted in individuals with hepatic or renal impairment, endocrine disorders, or concurrent pharmacotherapy affecting the pathways described above.
Ipamorelin — common questions
What is Ipamorelin and what is it used for in research?
How does Ipamorelin work?
What is the typical Ipamorelin research dose?
Where can I buy Ipamorelin in Thailand?
How fast can Ipamorelin be delivered in Thailand?
Citations
- Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998. PMID: 9849822
- Gobburu JV, et al. Pharmacokinetic-pharmacodynamic modeling of ipamorelin, a growth hormone releasing peptide, in human volunteers. Pharm Res. 1999. PMID: 10496658
References curated from PubMed. Additional literature summarised in the Thailand Peptides research library.